26 Comments
User's avatar
alaskachick's avatar

Why take a brand new drug? Why not just take safe, cheap, and effective Ivermectin? I don't get it.

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John (jc) Comeau's avatar

Because Ivermectin is off-patent and nobody is going to get rich from pushing it.

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Dr. Mike's avatar

Or it simply is ineffective in treating mod-severe Covid-19.

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John (jc) Comeau's avatar

What dosage did you try, and at what stage of disease? Its antiviral properties are best in the first 1 to 3 days, and its anti-inflammatory properties can be helpful in the later stages. Did you use at least .4mg/kg for at least 5 days?

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pf wagner's avatar

Try actually reading the studies, especially the meta study. Without question, it is safe and effective, unlike the mrna "vaccination."

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Dr. Mike's avatar

There is no peer reviewed literature reporting ivermectin trials that definitively establish any efficacy in the treatment of covid-19.

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Redpill's avatar

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

https://covid19criticalcare.com/wp-content/uploads/2021/06/Ivermectin_for_Prevention_and_Treatment_of.98040.pdf

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pf wagner's avatar

Are you really this ignorant?

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Mark Swarbrick's avatar

Are you kidding? You need to read the literature on the subject.

https://www.amzn.com/B09MDV4VT9

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Lee's avatar

Because ivermectin doesn't treat covid

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Betsy McDonel Herr, Ph.D.'s avatar

Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19

Santin, Scheim, McCullough, Yagisawa, Borody

https://pubmed.ncbi.nlm.nih.gov/34466270/

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metal's avatar

It's has a secondary function of being a zinc ionophore.

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pf wagner's avatar

as does HQC

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Mark Swarbrick's avatar

Ivermectin cured my wife, my daughter, my son, and many others and kept me from catching Covid at all.

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Steve Parker's avatar

Tell that to the 275,000 patients of MyFreeDoctor and the many thousands of others independent doctors using it

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Igor Chudov's avatar

Great article and the topic is amazing!

Check out other paxlovid articles:

On April 13, I brought up many people having rebounds with Paxlovid

https://igorchudov.substack.com/p/paxlovid-snake-oil-of-the-21st-century

Brian Mowrey wrote several great paxlovid articles giving some biomolecular details

https://unglossed.substack.com/

Paxlovid was never tested on the vaxxed, ON PURPOSE, and no one should be surprised that it does not work on the vaxed.

Ivermectin, as always, works great and costs 1/100 of Paxlovid cost. I treated my wife with it to amazing results, temp dropped to normal right away and no long covid afterwards

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Betsy McDonel Herr, Ph.D.'s avatar

Dr. Mobeen Syed, the FLCCC docs did warn about this problem. Paxlovid failure due to the narrow rather than broad range activity of the drug. Ivermectin still reigns supreme in the context of a full protocol that gives full spectrum and ongoing protection until well.

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Clayton Newberry's avatar

So far, everything about COVID, its vaccinations, and its vaccination promoters, is fishy. No need to hesitate being cynical, Doc. Listen to your gut instinct: There's alot more going on here than we have any idea. Follow the money. Follow the politics. And always keep in mind what a certain politician said: "Never let a crisis go to waste."

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Grundvilk's avatar

So, like I remarked, repetition of dosing seems reasonable -- like that already practiced with Ivermectin.

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Bill Stack's avatar

I made this comment in another article on this site but it’s even more relevant here. I read the original study on Paxlovid rebound , I believe it was in the New England Journal of Medicine as I get their regular email. It said the 5% rebound ( lower than in this article) was identical to the control group. The rebound effect, it would seem, is a characteristic of Covid. Paxlovid simply doesn’t prevent it.

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DWB's avatar

"vaccinated people are much less likely to be severely ill in the first place."

For how long? Meaning, more than a few months? At least a year? How many shots can a person withstand to keep up this 'protection'?

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JCStudResDoc94's avatar

i saw this 1st on twtr as well. in-between all the crowing about how fantastic it was (claimed to be). just incredible. the regulator & journals have long needed an overhaul. but the pandemic has turned cracks into canyons. -JC

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Grundvilk's avatar

From what I understand, the chemical binding between Paxlovid (or Ivermectin) and the ACE2 cell receptor assembly, the assembly that can help the virus to enter cells, is reversible (wears out) over time, so so-called 'rebound' would naturally be expected in its use. In the Ivermectin case, periodically repeated doses of the substance reportedly are used in order to assure continuation of therapeutic effect. Presumably, then, the same practice would therefore have to be used with Paxlovid as with Ivermectin to maintain its efficacy.

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Michael M H's avatar

The binding is reversible but the drug still occupies the ACE2 binding site some of the time. When it does occupy an ACE2 binding site that receptor is not available for the virus. The spread of the virus is slowed down and this helps the immune system. The rebound happens because the concentration of the drug declines and the spread of the remaining virus increases.

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pf wagner's avatar

"how did this not make it onto Paxlovid’s labeling information?" The FDA is owned by Big Pharma and both lie through their teeth for $$$.

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Bill Stack's avatar

I made this comment in another article on this site but it’s even more relevant here. I read the original study on Paxlovid rebound , I believe it was in the New England Journal of Medicine as I get their regular email. It said the 5% rebound ( lower than in this article) was identical to the control group. The rebound effect, it would seem, is a characteristic of Covid. Paxlovid simply doesn’t prevent it.

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